It may not be intuitive that a sample preparation step like DNA size selection would have a significant impact on downstream data analysis, but NGS users have proven that it does. Indeed, the precision of your size selection (or lack thereof) can make or break a genome assembly. Consider the alignment challenge for paired-end reads: […]
The post For Better NGS Assemblies, Use More Precise DNA Size Selection appeared first on Bitesize Bio.
A scene from the 90s hit sitcom Home Improvement about parenting and dealing with children’s problems has stuck with me for years. As he often did, the father figure, Tim Taylor, sought advice from his eccentric neighbor, Wilson. In this episode, Wilson’s point was that parents deal with little problems when their kids are little. […]
The post Thanking Hardship in Science: One Reason to Appreciate Struggle and Failure appeared first on Bitesize Bio.